SCHEMBL27468337

SCHEMBL27468337

O=C(OCl)C(Cl)(c1ccccc1)c1ccccc1.[Cu]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.59
KCNN4 O15554 1/20 0.44
TSHR P16473 2/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
MAPT P10636 3/20 0.36
KMT2A Q03164 2/20 0.36
CES1 P23141 1/20 0.36
CYP2C19 P33261 2/20 0.35
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
ALOX15 P16050 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27264055 0.98 CYP1A2 (0.61) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27953315 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27449855 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
Ammonia Solution, Strong SCHEMBL28235508 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL28052287 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27668566 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27558804 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27383842 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27720311 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27799952 0.96 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109879861-A A kind of method of indoline C7 acetoxylations 宁波大学 2019-06-14 CN disclosed
CN-108948214-A The new application of metal salt and the method for improving cellulose acetate stability 四川普什醋酸纤维素有限责任公司 2018-12-07 CN disclosed
CN-107047544-A The preparation method of plant specimen 卞陆杰 2017-08-18 CN disclosed
CN-106380438-A Preparation method of indoline derivative for synthesizing silodosin 江苏宇田医药有限公司 2017-02-08 CN disclosed
CN-102688760-B Fe3O4/CuO/pSiO2 catalyst and preparation method thereof UNIV BEIJING SCIENCE & TECH 2014-04-02 CN disclosed
CN-102688760-A Fe3O4/CuO/pSiO2 catalyst and preparation method thereof UNIV BEIJING SCIENCE & TECH 2012-09-26 CN disclosed
CN-1132634-C Process for preparation of slow-releasing material GUANGZHOU INST OF CHEMISTRY (CN) 2003-12-31 CN disclosed
CN-1319433-A Process for preparation of slow-releasing material GUANGZHOU INST OF CHEMISTRY (CN) 2001-10-31 CN disclosed