Tyrosine

Tyrosine

SCHEMBL27468643

CC(C)CC(N)C(=O)O.NC(CO)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.69
PTGS1 P23219 2/20 0.50
FOLH1 Q04609 1/20 0.50
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
XIAP P98170 1/20 0.50
KDM4E B2RXH2 1/20 0.48
USP2 O75604 1/20 0.48
EGFR P00533 1/20 0.48
LCK P06239 1/20 0.48
FYN P06241 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
ALOX15 P16050 1/20 0.48
HTR2A P28223 1/20 0.48
PTGS2 P35354 1/20 0.48
RECQL P46063 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TAAR1 Q96RJ0 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL25212292 0.96 SLC7A5 (0.63) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL1537211 0.94 SLC7A5 (0.77) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL302977 0.94 SLC7A5 (0.77) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL302978 0.94 SLC7A5 (0.77) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL18249967 0.94 SLC7A5 (0.77) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL3170725 0.91 SLC7A5 (0.73) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL2205393 0.91 SLC7A5 (0.73) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL11338514 0.90 SLC7A5 (0.71) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL11338506 0.90 SLC7A5 (0.71) SLC7A5PTGS1FOLH1ALPIPKM
Tyrosine SCHEMBL271922 0.89 SLC7A5 (0.86) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105254708-B A kind of anti-oxidant tripeptides of carrot seed and the preparation method and application thereof 福州大学 2019-03-12 CN disclosed
CN-100491394-C Anti-angiogenic polypeptides DAVID M WAISMAN KASSAM GEETHA (CA) 2009-05-27 CN disclosed
CN-1240712-C Method of preparing tyrosine-serine-leucine tripeptide KANGZHE PHARMACEUTICAL CO LTD (CN) 2006-02-08 CN disclosed
CN-1240712-C Method of preparing tyrosine-serine-leucine tripeptide KANGZHE PHARMACEUTICAL CO LTD (CN) 2006-02-08 CN disclosed
CN-1513871-A Method of preparing tyrosine-serine-leucine tripeptide 深圳市康哲药业股份有限公司 2004-07-21 CN disclosed
CN-1498223-A Anti-angiogenic polypeptides M 2004-05-19 CN disclosed
CN-1151761-A Subtilisin BPN' variants with reduced adsorption and increased hydrolysis PROCTER & GAMBLE (US) 1997-06-11 CN disclosed