SCHEMBL27469008

SCHEMBL27469008

C=C(O)CCOc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.58
RECQL P46063 2/20 0.58
ALDH1A1 P00352 2/20 0.58
TAAR1 Q96RJ0 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
TSHR P16473 1/20 0.49
PKM P14618 1/20 0.48
THRB P10828 1/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HTR1B P28222 2/20 0.47
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19890286 0.83 KCNA3 (0.54) KCNA3RECQLALDH1A1TAAR1CYP1A2
SCHEMBL11096752 0.83 KCNA3 (0.54) KCNA3RECQLALDH1A1TAAR1CYP1A2
SCHEMBL3293084 0.83 KCNA3 (0.54) KCNA3RECQLALDH1A1TAAR1CYP1A2
SCHEMBL1835409 0.83 KCNA3 (0.54) KCNA3RECQLALDH1A1TAAR1CYP1A2
SCHEMBL2357301 0.81 KCNA3 (0.52) KCNA3RECQLALDH1A1TAAR1CYP1A2
SCHEMBL44088 0.79 CYP1A2 (0.54) KCNA3RECQLALDH1A1CYP1A2CYP3A4
SCHEMBL183053 0.78 CYP1A2 (0.49) KCNA3RECQLALDH1A1TAAR1CYP1A2
Ethylene SCHEMBL29058163 0.78 KCNA3 (0.74) KCNA3RECQLALDH1A1TAAR1PKM
SCHEMBL10370308 0.77 KCNA3 (0.58) KCNA3RECQLALDH1A1TAAR1CYP1A2
SCHEMBL7030538 0.77 KCNA3 (0.58) KCNA3RECQLALDH1A1TAAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1088579-C Antiplaque oral composition COLGATE PALMOLIVE CO (US) 2002-08-07 CN disclosed
CN-1200025-A Antiplaque oral composition COLGATE PALMOLIVE CO (US) 1998-11-25 CN disclosed