SCHEMBL27469366

SCHEMBL27469366

NCc1cc(I)ccc1Nc1cc(F)ccc1-c1conc1O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TNIK Q9UKE5 1/20 0.31
MAP2K1 Q02750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6137910 0.84 IDO1 (0.41) TNIKMAP2K1
SCHEMBL27548849 0.78 TNIK (0.33) TNIKMAP2K1
SCHEMBL27563916 0.72 MAP2K1 (0.50) MAP2K1
SCHEMBL6137733 0.68 IDO1 (0.38) MAP2K1
SCHEMBL6137791 0.67 MAP2K1 (0.41) TNIKMAP2K1
SCHEMBL6137785 0.65 IDO1 (0.38)
SCHEMBL27453006 0.65
SCHEMBL6138084 0.65 MEN1 (0.44) TNIKMAP2K1
SCHEMBL6137805 0.64 IDO1 (0.38) TNIKMAP2K1
SCHEMBL6137778 0.64 IDO1 (0.38) TNIKMAP2K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1334807-A 1-heterocycle substd. diarylamines WARNER LAMBERT CO (US) 2002-02-06 CN claimed
CN-1149204-C 1-heterocyclic substituted diarylamines ��ʲ 2004-05-12 CN disclosed
CN-1334807-A 1-heterocycle substd. diarylamines WARNER LAMBERT CO (US) 2002-02-06 CN disclosed