⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127161 | 1.00 | — | — | |
| SCHEMBL29028 | 1.00 | — | — | |
| SCHEMBL13288513 | 0.75 | — | — | |
| SCHEMBL360998 | 0.75 | — | — | |
| SCHEMBL19378 | 0.72 | — | — | |
| SCHEMBL12903855 | 0.72 | — | — | |
| SCHEMBL14113208 | 0.71 | — | — | |
| SCHEMBL281735 | 0.71 | — | — | |
| SCHEMBL7558589 | 0.69 | TSHR (0.33) | — | |
| SCHEMBL9142636 | 0.69 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309055-B2 | PET radiotracers | HAMMERSMITH IMANET LIMITED (GB) | 2012-11-13 | — | — | US | disclosed |
| US-20120189547-A1 | [18F] LABELLED ANALOGUES OF FLUMAZENIL AS IN VIVO IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2012-07-26 | — | — | US | disclosed |
| US-8216548-B2 | Radiofluorination methods | GE HEALTHCARE AS (NO) | 2012-07-10 | — | — | US | disclosed |
| US-20120130122-A1 | PET RADIOTRACERS | HAMMERSMITH IMANET LIMITED (GB) | 2012-05-24 | — | — | US | disclosed |
| US-20120004404-A1 | RADIOLABELLING METHODS | HAMMERSMITH IMANET LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| US-20100233086-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100196270-A1 | RADIOFLUORINATION METHODS | GE HEALTHCARE AS (NO) | 2010-08-05 | — | — | US | disclosed |
| US-20100034740-A1 | RADIOFLUORINATION METHODS | GE HEALTHCARE AS (NO) | 2010-02-11 | — | — | US | disclosed |
| US-20090317328-A1 | TRICYCLIC OXAZEPINES AS IN VIVO IMAGING COMPOUNDS | ARSTAD ERIK | 2009-12-24 | — | — | US | disclosed |
| US-20090191129-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | Lantheus Biosciences Ltd. (GB) | 2009-07-30 | — | — | US | disclosed |
| US-20090130020-A1 | DIAGNOSTIC AGENTS FOR POSITRON EMISSION IMAGING USING F-18 RADIO-LABELED AMINO-ALCOHOLS | BAYER SCHERING PHARMA AG (DE) | 2009-05-21 | — | — | US | disclosed |
| US-20080292552-A1 | Pet Radiotracers | ARSTAD ERIK | 2008-11-27 | — | — | US | disclosed |
| US-20080177108-A1 | Phenyloxyaniline derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | US | disclosed |