SCHEMBL27469684

SCHEMBL27469684

Nc1cccc2c(=O)oc(=O)[nH]c12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 7/20 0.53
F2 P00734 1/20 0.52
CFD P00746 1/20 0.52
TDP1 Q9NUW8 3/20 0.50
POLB P06746 2/20 0.50
MCL1 Q07820 2/20 0.45
KDM4E B2RXH2 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
BLM P54132 1/20 0.45
ELANE P08246 2/20 0.44
RECQL P46063 1/20 0.42
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21658311 0.81 F2 (0.55) PARP1F2CFDPOLBMCL1
SCHEMBL2060660 0.78 F2 (0.52) F2CFDPOLBMCL1KDM4E
SCHEMBL30211329 0.78 F2 (0.52) PARP1F2CFDMCL1KDM4E
SCHEMBL15211017 0.78 F2 (0.52) PARP1F2CFDTDP1MCL1
SCHEMBL6739074 0.78 F2 (0.52) PARP1F2CFDMCL1KDM4E
SCHEMBL2061364 0.78 F2 (0.52) PARP1F2CFDMCL1MAPT
SCHEMBL28715626 0.78 F2 (0.52) F2CFDMCL1ELANEPDGFRA
SCHEMBL1904323 0.78 F2 (0.52) F2CFDPOLBMCL1KDM4E
SCHEMBL2484702 0.77 MCL1 (0.49) PARP1TDP1POLBMCL1
SCHEMBL31686101 0.77 MCL1 (0.49) PARP1TDP1POLBMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105283489-B Polymeric dispersants 巴斯夫欧洲公司 2019-02-12 CN disclosed
CN-107075243-A Novel polymer compositions and use of these polymer compositions as dispersants 巴斯夫欧洲公司 2017-08-18 CN disclosed
CN-105492492-A Novel polymers and the use of these as dispersants BASF SE 2016-04-13 CN disclosed
CN-105283489-A Novel polymeric dispersants BASF SE 2016-01-27 CN disclosed
CN-105073827-A Novel polymeric dispersants BASF SE 2015-11-18 CN disclosed
CN-104910298-A Hydrogenated nitrile rubber containing amino methyl group and method for producing the same LANXESS DEUTSCHLAND GMBH 2015-09-16 CN disclosed
CN-1165532-C Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors ���Ͽع����޹�˾ 2004-09-08 CN disclosed
CN-1320121-A Substituted 3-cyanoquinolines as protein tyrosine kinase inhibitors AMERICAN CYANAMID CO (US) 2001-10-31 CN disclosed