Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.75 |
| ▸ | CSNK1A1 | P48729 | 11/20 | 0.75 |
| ▸ | IKZF2 | Q9UKS7 | 14/20 | 0.60 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30707582 | 1.00 | CRBN (0.75) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30707716 | 0.90 | CRBN (0.76) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL27471282 | 0.90 | CRBN (0.76) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30707667 | 0.89 | CRBN (0.69) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30707584 | 0.88 | CRBN (0.74) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30707630 | 0.88 | CRBN (0.76) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL30213232 | 0.88 | CRBN (0.73) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL27387190 | 0.86 | CRBN (1.00) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30213332 | 0.86 | CRBN (0.73) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30707570 | 0.86 | CRBN (0.73) | CRBNCSNK1A1IKZF2GSPT1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244818-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |