⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8495214 | 0.97 | — | — | |
| SCHEMBL27997169 | 0.92 | — | — | |
| SCHEMBL2709324 | 0.88 | — | — | |
| SCHEMBL25154093 | 0.86 | TSHR (0.55) | — | |
| SCHEMBL4789833 | 0.86 | TSHR (0.72) | — | |
| SCHEMBL2000125 | 0.84 | — | — | |
| SCHEMBL8678748 | 0.83 | TSHR (0.68) | — | |
| SCHEMBL27299933 | 0.83 | TSHR (0.68) | — | |
| SCHEMBL1363023 | 0.81 | — | — | |
| SCHEMBL25154094 | 0.81 | TSHR (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755965-B1 | NOVEL IMIDAZOLE AMINES AS MODULATORS OF KINASE ACTIVITY | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-8263566-B2 | Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4″-or 4′-position | MERIAL LIMITED (US) | 2012-09-11 | — | — | US | disclosed |
| US-RE43244-E1 | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | H. LUNDBECK A/S (DK) | 2012-03-13 | — | — | US | disclosed |
| US-RE42802-E1 | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | H. LUNDBECK A/S (DK) | 2011-10-04 | — | — | US | disclosed |
| US-20110230429-A1 | AVERMECTIN B1 AND AVERMECTIN B1 MONOSACCHARIDE DERIVATIVES HAVING AN ALKOXYMETHYL SUBSTITUENT IN THE 4\"-OR 4'-POSITION | SYNGENTA CROP PROTECTION, LLC (US) | 2011-09-22 | — | — | US | disclosed |
| CN-100383126-C | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | LUNDBECK AS KOPENHAGEN VALBY H (DK) | 2008-04-23 | — | — | CN | disclosed |
| CN-1781910-A | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | LUNDBECK AS KOPENHAGEN VALBY H (DK) | 2006-06-07 | — | — | CN | disclosed |
| US-6998405-B2 | Parkinson's and Huntington's disease; psychoses, impotence, renal or heart failure, schizophrenia | H. LUNDBECK A/S (DK) | 2006-02-14 | — | — | US | disclosed |
| CN-1234351-C | Phenylethylamines and fused ring variants as prodrugs of catecholamines and uses thereof | LUNDBECK & CO AS H (DK) | 2006-01-04 | — | — | CN | disclosed |
| EP-1274411-B1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | LUNDBECK & CO AS H (DK) | 2005-07-27 | — | — | EP | disclosed |
| CN-1450894-A | Phenylethylamines and fused ring variants as prodrugs of catecholamines and uses thereof | AXON BIOCHEMICALS BV (NL) | 2003-10-22 | — | — | CN | disclosed |
| US-20030087948-A1 | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | H. LUNDBECK A/S (DK) | 2003-05-08 | — | — | US | disclosed |
| EP-1274411-A1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | Axon Biochemicals B.V. (NL) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001078713-A1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | AXON BIOCHEMICALS B.V. (NL) | 2001-10-25 | — | — | WO | disclosed |
| US-6165378-A | Polysaccharide derivative/magnetic metal oxide composite | MEITO SANGYO KABUSHIKI KAISHA (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0928809-A1 | POLYSACCHARIDE DERIVATIVE/MAGNETIC METAL OXIDE COMPOSITE | MEITO SANGYO KABUSHIKI KAISHA (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0161218-B1 | BENZO-(PYRANO AND THIOPYRANO)PYRIDINES | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
| US-4721787-A | CONDENSATION, REDUCTION, DEHYDRATION | CIBA-GEIGY CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4604397-A | Certain benzo-(pyrano and thiopyrano)-pyridines, useful as CNS agents | CIBA-GEIGY CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0161218-A2 | Benzo-(pyrano and thiopyrano)pyridines | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |