Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892447 | 0.94 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL7893510 | 0.94 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL7895688 | 0.94 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL7347255 | 0.90 | MAPK1 (0.43) | MAPK1MEN1LMNAHPGDKMT2A | |
| SCHEMBL31194643 | 0.83 | MAPK1 (0.44) | MAPK1MEN1LMNAHPGDKMT2A | |
| SCHEMBL27492051 | 0.83 | PDPK1 (0.36) | SMN1; SMN2GAAPDPK1RIPK2LCK | |
| SCHEMBL7885922 | 0.77 | CNR1 (0.36) | MEN1KMT2ASMN1; SMN2KDM4EPDPK1 | |
| SCHEMBL7893996 | 0.77 | CNR1 (0.36) | MEN1KMT2ASMN1; SMN2KDM4EPDPK1 | |
| SCHEMBL7895740 | 0.77 | CNR1 (0.36) | MEN1KMT2ASMN1; SMN2KDM4EPDPK1 | |
| SCHEMBL18281310 | 0.77 | GAA (0.57) | MAPK1MEN1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177960-A | 6-substituted pyrazolo (3, 4 -d) pyrimidin -4 ones and compositions and methods of use thereof | SANOFI WINTHROP INC (US) | 1998-04-01 | — | — | CN | disclosed |