Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092028 | 0.80 | S1PR3 (0.44) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL29092023 | 0.80 | S1PR3 (0.44) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9538517 | 0.77 | S1PR2 (0.44) | GLB1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL18925047 | 0.76 | GLB1 (0.38) | GLB1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL27400264 | 0.74 | S1PR2 (0.42) | GLB1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL24059097 | 0.71 | S1PR2 (0.41) | GLB1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL16228223 | 0.69 | S1PR2 (0.40) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL20464903 | 0.68 | GLB1 (0.44) | GLB1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL12227571 | 0.68 | — | — | |
| SCHEMBL13764929 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190390-A | Nitric oxide synthase inhibitors derived from cyclic amidines | SEARLE & CO (US) | 1998-08-12 | — | — | CN | disclosed |