Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.47 |
| ▸ | HTR1B | P28222 | 5/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484443 | 0.93 | HTR1D (0.54) | HTR1DHTR1BCHRM2DRD2CCR2 | |
| SCHEMBL27483641 | 0.88 | HTR1D (0.54) | HTR1DHTR1B | |
| SCHEMBL27498570 | 0.83 | HTR1D (0.51) | HTR1DHTR1BCHRM2DRD2CCR2 | |
| SCHEMBL7484437 | 0.80 | HTR1D (0.55) | HTR1DHTR1BCHRM2DRD2CCR2 | |
| SCHEMBL7479253 | 0.80 | HTR1D (0.64) | HTR1DHTR1B | |
| SCHEMBL27498200 | 0.80 | HTR1D (0.49) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL27498199 | 0.79 | HTR1D (0.48) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7483818 | 0.78 | HTR1D (0.57) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7487565 | 0.77 | HTR1D (0.55) | HTR1DHTR1BCHRM2DRD2CCR2 | |
| SCHEMBL27498204 | 0.77 | HTR1D (0.59) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184425-A | 5-substituted-3- (1,2,3, 6-tetrahydropyridin-4-yl) -and 3- (piperidin-4-yl) -1H-indoles, 5-HT1FAgonists | LILLY CO ELI (US) | 1998-06-10 | — | — | CN | disclosed |