Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17634027 | 0.93 | — | — | |
| SCHEMBL4819466 | 0.93 | — | — | |
| SCHEMBL21088951 | 0.93 | — | — | |
| SCHEMBL56901 | 0.93 | — | — | |
| Water SCHEMBL28043193 | 0.90 | CYP1A2 (0.41) | CYP1A2 | |
| Methylamine SCHEMBL28038298 | 0.90 | CYP1A2 (0.41) | CYP1A2 | |
| SCHEMBL10454219 | 0.90 | CYP1A2 (0.41) | CYP1A2 | |
| Hydrogen Peroxide SCHEMBL27513983 | 0.88 | CYP1A2 (0.48) | CYP1A2 | |
| SCHEMBL24843672 | 0.85 | CYP1A2 (0.36) | CYP1A2 | |
| SCHEMBL10775419 | 0.85 | CYP1A2 (0.36) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1626069-A | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of diabetic retinopathy | WARNER LAMBERT CO (US) | 2005-06-15 | — | — | CN | disclosed |
| CN-1170811-C | Inhibitors of branched chain amino acid dependent aminotransferases and their use in the treatment of diabetic retinopathy | ��ʲ | 2004-10-13 | — | — | CN | disclosed |
| CN-1344245-A | Inhibitors of branched chain amino acid dependent aminotransferases and their use in the treatment of diabetic retinopathy | WARNER LAMBER CO (US) | 2002-04-10 | — | — | CN | disclosed |