Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499046 | 0.99 | TSHR (0.47) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL27519992 | 0.99 | TSHR (0.47) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL7176995 | 0.96 | TSHR (0.45) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL27499352 | 0.96 | TSHR (0.44) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL7182417 | 0.95 | TSHR (0.46) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL7184554 | 0.95 | TSHR (0.46) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL7182655 | 0.95 | TSHR (0.46) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL7186690 | 0.95 | TSHR (0.46) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL7189184 | 0.93 | TSHR (0.43) | TSHRTP53CYP3A4MAPK1LMNA | |
| SCHEMBL27486010 | 0.91 | TSHR (0.47) | TSHRTP53CYP3A4MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |