Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486121 | 0.86 | — | — | |
| SCHEMBL8078986 | 0.85 | KDM4E (0.51) | ALDH1A1MAPT | |
| Bromide SCHEMBL8078981 | 0.84 | KDM4E (0.50) | ALDH1A1MAPT | |
| SCHEMBL8627004 | 0.82 | GRIN1 (0.49) | — | |
| SCHEMBL27499500 | 0.82 | — | — | |
| Bromide SCHEMBL8086899 | 0.82 | — | — | |
| SCHEMBL8565598 | 0.81 | — | — | |
| SCHEMBL8565720 | 0.81 | — | — | |
| SCHEMBL8570362 | 0.80 | — | — | |
| Bromide SCHEMBL8090535 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193968-A | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | NOVARTIS AG (CH) | 1998-09-23 | — | — | CN | claimed |
| CN-1197452-A | Azetidinone derivatives for treatment of atherosclerosis | SMITHKLINE BEECHAM PLC (GB) | 1998-10-28 | — | — | CN | disclosed |