Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528431 | 0.99 | PPARA (0.48) | PPARATSHRTP53CYP3A4MAPK1 | |
| SCHEMBL27528453 | 0.99 | PPARA (0.48) | PPARATSHRTP53CYP3A4MAPK1 | |
| SCHEMBL27499655 | 0.96 | PPARA (0.44) | PPARATSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7179748 | 0.95 | PPARA (0.46) | PPARATSHRTP53CYP3A4MAPK1 | |
| SCHEMBL7178050 | 0.94 | PPARA (0.48) | PPARATSHRTP53CYP3A4MAPK1 | |
| SCHEMBL7181196 | 0.94 | PPARA (0.48) | PPARATSHRTP53CYP3A4MAPK1 | |
| SCHEMBL7182799 | 0.94 | PPARA (0.48) | PPARATSHRTP53CYP3A4MAPK1 | |
| SCHEMBL7175866 | 0.94 | PPARA (0.48) | PPARATSHRTP53CYP3A4MAPK1 | |
| SCHEMBL27500280 | 0.92 | PPARA (0.42) | PPARATSHRTP53CYP3A4MAPK1 | |
| SCHEMBL7189067 | 0.92 | PPARA (0.44) | PPARATSHRCYP3A4MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |