Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486103 | 1.00 | ACE (0.62) | ACEACE2LTA4HALDH1A1SMN1; SMN2 | |
| SCHEMBL6442128 | 0.91 | ACE (0.74) | ACEACE2LTA4H | |
| SCHEMBL6442125 | 0.91 | ACE (0.74) | ACEACE2LTA4H | |
| SCHEMBL18085979 | 0.88 | ACE (0.64) | ACEACE2 | |
| SCHEMBL6436088 | 0.85 | ACE (0.67) | ACEACE2LTA4H | |
| SCHEMBL6439093 | 0.85 | ACE (0.62) | ACEACE2 | |
| SCHEMBL8257221 | 0.83 | ACE (0.56) | ACEACE2 | |
| SCHEMBL21347513 | 0.83 | ACE (0.56) | ACEACE2 | |
| SCHEMBL19685446 | 0.83 | ACE (0.56) | ACEACE2 | |
| SCHEMBL7855038 | 0.82 | KDM4E (0.58) | ACEACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151166-A | 3-Amino-2-oxo-1-piperidineacetic acid derivatives as enzyme inhibitors | CORVAS INT INC (US) | 1997-06-04 | — | — | CN | disclosed |