Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555475 | 0.79 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL27489293 | 0.72 | ESR1 (0.33) | ESR1HIF1APTPN1RECQLKMT2A | |
| SCHEMBL27487187 | 0.70 | — | — | |
| SCHEMBL27720625 | 0.69 | — | — | |
| SCHEMBL17922942 | 0.68 | — | — | |
| SCHEMBL27472021 | 0.67 | — | — | |
| SCHEMBL27549972 | 0.67 | — | — | |
| SCHEMBL27471560 | 0.66 | — | — | |
| SCHEMBL27487544 | 0.66 | — | — | |
| SCHEMBL27488965 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100430049-C | Depressant of functions developed by molecule | SHOZO KOYAMA (JP) | 2008-11-05 | — | — | CN | disclosed |
| CN-1162918-A | Depressant of functions developed by molecule | KOYAMA SHOZO (JP) | 1997-10-22 | — | — | CN | disclosed |