Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078889 | 0.86 | HTT (0.39) | NQO2POLB | |
| SCHEMBL8086933 | 0.83 | SIRT2 (0.35) | SIRT2 | |
| SCHEMBL27440732 | 0.82 | NQO2 (0.38) | SIRT2NQO2POLB | |
| SCHEMBL8086008 | 0.78 | TLR8 (0.34) | SIRT2 | |
| SCHEMBL5973317 | 0.77 | NQO2 (0.40) | NQO2POLB | |
| SCHEMBL8078887 | 0.77 | POLB (0.41) | NQO2POLB | |
| SCHEMBL27513154 | 0.76 | HRH4 (0.32) | — | |
| SCHEMBL5973535 | 0.72 | POLB (0.41) | NQO2POLB | |
| SCHEMBL8078869 | 0.71 | POLB (0.34) | NQO2POLB | |
| SCHEMBL5973965 | 0.70 | HRH4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193968-A | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | NOVARTIS AG (CH) | 1998-09-23 | — | — | CN | claimed |