Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466284 | 0.86 | SLC6A2 (0.37) | TDP1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL4630047 | 0.78 | TDP1 (0.37) | BACE1TDP1PLA2G7LMNAMEN1 | |
| SCHEMBL4630553 | 0.77 | TACR2 (0.37) | BACE1TDP1PLA2G7LMNATACR2 | |
| SCHEMBL4630747 | 0.77 | TDP1 (0.36) | BACE1TDP1PLA2G7LMNAMEN1 | |
| SCHEMBL4631282 | 0.71 | TACR2 (0.58) | TDP1TACR2ALDH1A1 | |
| SCHEMBL27390996 | 0.70 | TACR2 (0.45) | LMNACYP1A2POLBMAPK1TACR2 | |
| SCHEMBL4630746 | 0.69 | TACR2 (0.36) | TDP1LMNAKMT2APOLBTACR2 | |
| SCHEMBL4630781 | 0.65 | SLC6A2 (0.40) | TDP1LMNATACR2 | |
| SCHEMBL7482580 | 0.64 | TDP1 (0.42) | BACE1TDP1LMNAKMT2AGAA | |
| SCHEMBL8153966 | 0.64 | TDP1 (0.42) | BACE1TDP1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1821241-A | Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same | SANOFI SA (FR) | 2006-08-23 | — | — | CN | disclosed |
| CN-1636983-A | Substituted heterocyclic compounds | SANOFI AVENTIS (FR) | 2005-07-13 | — | — | CN | disclosed |
| CN-1202093-C | Substituted heterocyclic compounds | SANOFI AVENTIS (FR) | 2005-05-18 | — | — | CN | disclosed |
| CN-1179954-C | Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ��ŵ�Ѻϳ�ʵ���� | 2004-12-15 | — | — | CN | disclosed |
| CN-1502612-A | Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ��ŵ�Ѻϳ�ʵ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1321639-A | Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHESIZING LAB (FR) | 2001-11-14 | — | — | CN | disclosed |