Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19059646 | 0.74 | SMN1; SMN2 (0.35) | KCNN4CNR1CNR2GAAL3MBTL1 | |
| SCHEMBL27641579 | 0.73 | TSHR (0.41) | KCNN4GAAMEN1KMT2AHSP90AA1 | |
| SCHEMBL26053254 | 0.73 | SMN1; SMN2 (0.36) | CNR1CNR2GAAMEN1KMT2A | |
| SCHEMBL19965676 | 0.72 | CNR2 (0.40) | CNR1CNR2GAAPSMD14HSP90AA1 | |
| SCHEMBL4284381 | 0.71 | ESR1 (0.38) | KCNN4GAASMN1; SMN2CACNA1GHTR7 | |
| SCHEMBL22435799 | 0.71 | CNR2 (0.41) | CNR1CNR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20097921 | 0.71 | CNR2 (0.42) | CNR1CNR2GAAPSMD14HSP90AA1 | |
| Ammonia Solution, Strong SCHEMBL11757631 | 0.71 | HSP90AA1 (0.40) | CNR1CNR2GAAMEN1KMT2A | |
| SCHEMBL21339358 | 0.70 | SMN1; SMN2 (0.35) | CNR1CNR2GAAMEN1KMT2A | |
| SCHEMBL30526183 | 0.70 | HSP90AA1 (0.42) | KCNN4CNR1CNR2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193748-C | Gardos channel antagonists | ICAGEN INC (US) | 2005-03-23 | — | — | CN | disclosed |
| CN-1344158-A | Gardos channel antagonists | ICAGEN INC (US) | 2002-04-10 | — | — | CN | disclosed |