Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL27634612 | 0.97 | TSHR (0.61) | TSHRCES2CES1MAPTPARP1 | |
| Chlorobenzene SCHEMBL9576941 | 0.94 | TSHR (0.65) | TSHRCES2CES1MAPTPARP1 | |
| Chlorobenzene SCHEMBL27555909 | 0.89 | TSHR (0.58) | TSHRCES2CES1MAPTPARP1 | |
| Chlorobenzene SCHEMBL10495752 | 0.89 | TSHR (0.58) | TSHRCES2CES1MAPTPARP1 | |
| Chlorobenzene SCHEMBL29172530 | 0.88 | TSHR (0.73) | TSHRCES2CES1MAPTL3MBTL1 | |
| Chlorobenzene SCHEMBL2533883 | 0.88 | TSHR (0.73) | TSHRCES2CES1MAPTL3MBTL1 | |
| Chlorobenzene SCHEMBL27620795 | 0.88 | TSHR (0.73) | TSHRCES2CES1MAPTL3MBTL1 | |
| Chlorobenzene SCHEMBL28868946 | 0.86 | TSHR (0.48) | TSHRCES2CES1MAPTPARP1 | |
| Chlorobenzene SCHEMBL28280446 | 0.86 | TSHR (0.61) | TSHRCES2CES1MAPTPARP1 | |
| Chlorobenzene SCHEMBL28956847 | 0.85 | TSHR (0.69) | TSHRCES2CES1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106727540-A | A kind of application of the 1,3,4 thiadiazoles disulfide compounds containing phenylurea based structures | 天津理工大学 | 2017-05-31 | — | — | CN | claimed |
| CN-101993416-A | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | claimed |
| CN-1213715-C | Antimicrobial caries-detecting composition | KURARAY CO (JP) | 2005-08-10 | — | — | CN | claimed |
| CN-1192015-C | Cell adhesion inhibitors | BIOGEN INC (US) | 2005-03-09 | — | — | CN | claimed |
| CN-1204505-A | Antimicrobial caries-detecting composition | KURARAY CO (JP) | 1999-01-13 | — | — | CN | claimed |
| CN-109661250-A | Medical devices for treating sinuses and/or ears and methods of use thereof | 西纳塞弗医疗有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-104955459-B | Substituted indoles -5- amphyl and its treatment use | 南特知识产权控股有限责任公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-108712904-A | The solid form of two Fluorakil 100s of 2- (4- chlorphenyls)-N- ((2- (2,6- dioxopiperidine -3- bases) -1- oxoisoindolines -5- bases) methyl) -2,2- and its pharmaceutical composition and purposes | 细胞基因公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-108430473-A | Antiproliferative compounds and pharmaceutical compositions and uses thereof | 细胞基因公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-105101959-B | Cyclic sulfonamide-containing derivatives as hedgehog signaling pathway inhibitors | 南特知识产权控股有限责任公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107847505-A | MULTILAMELLAR LIPID VESICLE COMPOSITIONS AND METHODS OF USE | 威登卓制药公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-106957275-A | The triazole compound of 2 alkyl-dithio, 5 substituted benzene urea groups 1,2,4 and its application | 天津理工大学 | 2017-07-18 | — | — | CN | disclosed |
| CN-101309587-A | Oil-in-water formulations of avermectins | CHEMINOVA AS (DK) | 2008-11-19 | — | — | CN | disclosed |
| CN-1910172-A | 3- (dihydro (tetrahydro) isoquinolin-1-yl) quinoline compounds | SANKYO AGRO CO LTD (JP) | 2007-02-07 | — | — | CN | disclosed |
| CN-1213715-C | Antimicrobial caries-detecting composition | KURARAY CO (JP) | 2005-08-10 | — | — | CN | disclosed |
| CN-1209678-C | Silver halide photographic emulsion contg. methylidyne compound, and photographic material using said emulsion | FUJI PHOTO FILM CO LTD (JP) | 2005-07-06 | — | — | CN | disclosed |
| CN-1165272-C | Antimicrobial caries detecting composition | �����ɷ� | 2004-09-08 | — | — | CN | disclosed |
| CN-1346628-A | Antimicrobial caries detecting composition | KURARAY CO (JP) | 2002-05-01 | — | — | CN | disclosed |
| CN-1324005-A | Silver halide photographic emulsion contg. methylidyne compound, and photographic material using said emulsion | FUJI PHOTO FILM CO LTD (JP) | 2001-11-28 | — | — | CN | disclosed |
| CN-1204505-A | Antimicrobial caries-detecting composition | KURARAY CO (JP) | 1999-01-13 | — | — | CN | disclosed |