Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877438 | 0.83 | HTR2A (0.56) | HTR2ABCHEACHE | |
| SCHEMBL5820544 | 0.83 | HTR2A (0.50) | HTR2ABCHEACHE | |
| SCHEMBL6060774 | 0.82 | HTR2A (0.54) | HTR2ABCHEACHE | |
| SCHEMBL6060938 | 0.82 | HTR2A (0.54) | HTR2ABCHEACHE | |
| SCHEMBL6060761 | 0.82 | HTR2A (0.54) | HTR2ABCHEACHE | |
| SCHEMBL407781 | 0.82 | HTR2A (0.54) | HTR2ABCHEACHE | |
| SCHEMBL6061696 | 0.82 | HTR2A (0.54) | HTR2ABCHEACHE | |
| SCHEMBL6061312 | 0.82 | HTR2A (0.54) | HTR2ABCHEACHE | |
| SCHEMBL2786275 | 0.82 | HTR2A (0.48) | HTR2ABCHEACHE | |
| SCHEMBL6060915 | 0.82 | HTR2A (0.54) | HTR2ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1209803-A | Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method therefor | BRISTOL MYERS SQUIBB CO (US) | 1999-03-03 | — | — | CN | disclosed |