Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 4/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762560 | 0.97 | TP53 (0.44) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL14161715 | 0.97 | TP53 (0.44) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL4165736 | 0.89 | — | — | |
| SCHEMBL18793695 | 0.89 | — | — | |
| SCHEMBL4157546 | 0.89 | — | — | |
| SCHEMBL18638206 | 0.78 | EPHX1 (0.36) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL5509761 | 0.76 | EPHX1 (0.40) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL16316581 | 0.76 | EPHX1 (0.40) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL13416816 | 0.76 | EPHX1 (0.40) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL19538503 | 0.76 | TP53 (0.48) | TP53KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1113436-A | Potentiation of drug response | LILLY CO ELI (US) | 1995-12-20 | — | — | CN | disclosed |