Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.76 |
| ▸ | ITGB2 | P05107 | 16/20 | 0.76 |
| ▸ | ICAM1 | P05362 | 16/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197693 | 1.00 | ITGAL (0.76) | ITGALITGB2ICAM1 | |
| SCHEMBL6198654 | 0.92 | ITGAL (0.75) | ITGALITGB2ICAM1 | |
| SCHEMBL27475646 | 0.92 | ITGAL (0.75) | ITGALITGB2ICAM1 | |
| SCHEMBL6199518 | 0.89 | ITGAL (0.72) | ITGALITGB2ICAM1 | |
| SCHEMBL27473568 | 0.88 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL27475299 | 0.86 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL6198458 | 0.86 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL27473967 | 0.86 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL6196029 | 0.82 | ITGAL (0.91) | ITGALITGB2ICAM1 | |
| SCHEMBL6198130 | 0.82 | ITGAL (0.74) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | claimed |
| CN-1680338-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | disclosed |