Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.68 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2166546 | 0.93 | CHRM2 (0.79) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL27556306 | 0.90 | CHRM2 (0.66) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL27507223 | 0.89 | CHRM2 (0.70) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL27491765 | 0.89 | CHRM2 (0.70) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL27491412 | 0.89 | CHRM2 (0.86) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL27506822 | 0.89 | CHRM2 (0.70) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL27507638 | 0.89 | CHRM2 (0.86) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL27506013 | 0.87 | CHRM2 (0.65) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| Hydrochloric Acid SCHEMBL27498480 | 0.87 | CHRM2 (0.83) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL27492480 | 0.87 | CHRM2 (0.67) | CHRM2CHRM1CHRM3ADRB2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1690041-A | Novel derivatives of 3,3-diphenylpropylamines | SANOL ARZNEI SCHWARZ GMBH (DE) | 2005-11-02 | — | — | CN | claimed |
| CN-1354737-A | Novel 3, 3-diphenylpropylamine derivatives | SANOL ARZNEI SCHWARZ GMBH (DE) | 2002-06-19 | — | — | CN | claimed |
| CN-100491336-C | Novel derivatives of 3,3-diphenylpropylamines | SANOL ARZNEI SCHWARZ GMBH (DE) | 2009-05-27 | — | — | CN | disclosed |
| CN-1690041-A | Novel derivatives of 3,3-diphenylpropylamines | SANOL ARZNEI SCHWARZ GMBH (DE) | 2005-11-02 | — | — | CN | disclosed |
| CN-1207268-C | 3, 3-diphenylpropylamine derivatives | SANOL ARZNEI SCHWARZ GMBH (DE) | 2005-06-22 | — | — | CN | disclosed |
| CN-1354737-A | Novel 3, 3-diphenylpropylamine derivatives | SANOL ARZNEI SCHWARZ GMBH (DE) | 2002-06-19 | — | — | CN | disclosed |