Benzophenone

Benzophenone

SCHEMBL27490408

O=C(c1ccccc1)c1ccccc1.O=[N+]([O-])c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.79

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.79
MAPK1 P28482 1/20 0.79
SRD5A2 P31213 2/20 0.74
CES1 P23141 2/20 0.74
CES2 O00748 1/20 0.74
LMNA P02545 2/20 0.66
GAA P10253 1/20 0.66
ALOX5 P09917 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.63
TDP1 Q9NUW8 2/20 0.63
ALDH1A1 P00352 4/20 0.62
MEN1 O00255 1/20 0.62
NPC1 O15118 1/20 0.62
MITF O75030 1/20 0.62
RAB9A P51151 1/20 0.62
KMT2A Q03164 1/20 0.62
BCHE P06276 1/20 0.59
MAOB P27338 1/20 0.59
MAPT P10636 1/20 0.58
CA1 P00915 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL28231509 0.98 POLB (0.82) POLBMAPK1SRD5A2CES1CES2
SCHEMBL229627 0.98 POLB (0.82) POLBMAPK1SRD5A2CES1CES2
Phosphine SCHEMBL28037976 0.96 POLB (0.79) POLBMAPK1SRD5A2CES1CES2
SCHEMBL28218378 0.96 POLB (0.79) POLBMAPK1SRD5A2CES1CES2
SCHEMBL27787062 0.96 POLB (0.79) POLBMAPK1SRD5A2CES1CES2
Methane SCHEMBL29286698 0.96 POLB (0.79) POLBMAPK1SRD5A2CES1CES2
Bicarbonate SCHEMBL28244785 0.96 POLB (0.79) POLBMAPK1SRD5A2CES1CES2
Ammonia Solution, Strong SCHEMBL27306146 0.96 POLB (0.79) POLBMAPK1SRD5A2CES1CES2
Hydrogen Sulfide SCHEMBL28154722 0.96 POLB (0.79) POLBMAPK1SRD5A2CES1CES2
Hydrochloric Acid SCHEMBL28168308 0.96 POLB (0.79) POLBMAPK1SRD5A2CES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1161397-C Polydiquinoline ketonic ether ketone with pendant sulfonate radical and its prepn. 上海交通大学 2004-08-11 CN disclosed
CN-1324880-A Polyether ketone with pendant sulfonate radical and pendant carboxylate radical and its prepn. UNIV SHANGHAI JIAOTONG (CN) 2001-12-05 CN disclosed
CN-1324881-A Polydiquinoline ketonic ether ketone with pendant sulfonate radical and its prepn. UNIV SHANGHAI JIAOTONG (CN) 2001-12-05 CN disclosed