SCHEMBL27490477

SCHEMBL27490477

NCC(N)c1cccnn1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
GOT1 P17174 1/20 0.38
P2RX7 Q99572 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12495185 0.82 CYP1A2 (0.42) CYP1A2GOT1P2RX7
SCHEMBL3712034 0.79 HTR2A (0.54) CYP1A2
SCHEMBL14152790 0.79 AAK1 (0.39) CYP1A2GOT1P2RX7
SCHEMBL14152483 0.79 AAK1 (0.39) CYP1A2GOT1P2RX7
SCHEMBL14151586 0.79 AAK1 (0.39) CYP1A2GOT1P2RX7
SCHEMBL12495184 0.78 TAAR1 (0.41) CYP1A2GOT1P2RX7
SCHEMBL3712032 0.77 CYP1A2 (0.46) CYP1A2
SCHEMBL22849136 0.74
SCHEMBL4417042 0.74
SCHEMBL4704366 0.72 SLC6A2 (0.47) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1209063-A Vitronection receptor antagonists SMITHKLINE BEECHAM CORP (US) 1999-02-24 CN disclosed