Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.59 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913326 | 0.84 | CYP3A4 (0.69) | CYP3A4SLC7A5NLN | |
| SCHEMBL13331622 | 0.78 | CYP3A4 (0.69) | CYP3A4SLC7A5NLN | |
| SCHEMBL18162790 | 0.78 | CYP3A4 (0.69) | CYP3A4SLC7A5NLN | |
| SCHEMBL27946609 | 0.78 | CYP3A4 (0.69) | CYP3A4SLC7A5NLN | |
| SCHEMBL6957266 | 0.78 | CYP3A4 (0.69) | CYP3A4SLC7A5NLN | |
| SCHEMBL27776881 | 0.78 | NLN (0.79) | NLN | |
| Histidine SCHEMBL25362582 | 0.77 | CYP3A4 (0.97) | CYP3A4SLC7A5 | |
| Histidine SCHEMBL30109345 | 0.77 | CYP3A4 (0.97) | CYP3A4SLC7A5 | |
| SCHEMBL27450330 | 0.76 | CYP3A4 (0.67) | CYP3A4SLC7A5NLN | |
| SCHEMBL4525493 | 0.76 | CA1 (0.72) | CYP3A4SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1338456-A | Benzodiazepine compound containing imidazole propionamido and preparation method and application thereof | INST OF MEDICAL MATERIALS CHIN (CN) | 2002-03-06 | — | — | CN | claimed |
| CN-1179752-C | Benzodiazepine * compound containing imidazole propionamido and its preparation method and use | 中国医学科学院药物研究所 | 2004-12-15 | — | — | CN | disclosed |
| CN-1338456-A | Benzodiazepine compound containing imidazole propionamido and preparation method and application thereof | INST OF MEDICAL MATERIALS CHIN (CN) | 2002-03-06 | — | — | CN | disclosed |