Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 13/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 11/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 11/20 | 0.49 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490239 | 0.94 | ITGAL (0.52) | ITGALITGB2ICAM1ANPEPMMP2 | |
| SCHEMBL6197886 | 0.92 | ITGB2 (0.64) | ITGALITGB2ICAM1 | |
| SCHEMBL27473968 | 0.89 | ITGAL (0.65) | ITGALITGB2ICAM1 | |
| SCHEMBL6201501 | 0.89 | ITGAL (0.65) | ITGALITGB2ICAM1 | |
| SCHEMBL27475644 | 0.87 | ITGAL (0.49) | ITGALITGB2ICAM1ANPEPMMP2 | |
| SCHEMBL27475643 | 0.86 | ITGAL (0.60) | ITGALITGB2ICAM1ANPEPMMP2 | |
| SCHEMBL7616863 | 0.86 | ITGAL (0.49) | ITGALITGB2ICAM1ANPEPMMP2 | |
| SCHEMBL27551783 | 0.84 | ITGB2 (0.65) | ITGALITGB2ICAM1 | |
| SCHEMBL6199024 | 0.84 | ITGAL (0.51) | ITGALITGB2ICAM1ANPEPMMP2 | |
| SCHEMBL7847222 | 0.84 | ITGAL (0.62) | ITGALITGB2ICAM1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | claimed |
| CN-1955164-A | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LAB (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1680338-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | disclosed |