SCHEMBL27498802

SCHEMBL27498802

OC1CC2=CC=CCC2C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16415862 0.82 ESR2 (0.31)
SCHEMBL2360998 0.77
SCHEMBL5889192 0.75
SCHEMBL12656250 0.75
SCHEMBL10320985 0.75
SCHEMBL7856504 0.73
SCHEMBL8071462 0.72 FYN (0.33)
SCHEMBL10320188 0.72
SCHEMBL23183086 0.71
SCHEMBL10318955 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1238362-C 'Pi' complex compounds BAYER AG (DE) 2006-01-25 CN disclosed
CN-1169792-C Substituted vinylpyridine derivatives and medicaments containing them ������ҩ��ʽ���� 2004-10-06 CN disclosed
CN-1100054-C Process for preparing HIV protease inhibitors from (2S) -4-picolyl-2-piperazine-tert-butylcarboxamide MERCK & CO INC (US) 2003-01-29 CN disclosed
CN-1093132-C Metallocene compounds BAYER AG (DE) 2002-10-23 CN disclosed
CN-1284960-A Pi complex compound BAYER AG (DE) 2001-02-21 CN disclosed
CN-1267656-A Process for producing indene compound adapted for being as metallocene ligand MONTELL TECHNOLOGY COMPANY BV (NL) 2000-09-27 CN disclosed
CN-1052736-C Process for the preparation of amorphous propylene polymers MONTELL TECHNOLOGY COMPANY BV (NL) 2000-05-24 CN disclosed
CN-1046727-C HIV protease inhibitors MERCK & CO INC (US) 1999-11-24 CN disclosed
CN-1229410-A Metallocene compounds BAYER AG (DE) 1999-09-22 CN disclosed
CN-1206407-A Substituted vinylpyridine derivatives and medicaments containing them SS PHARMACEUTICAL CO (JP) 1999-01-27 CN disclosed
CN-1183779-A Process for preparing HIV protease inhibitors from (2S) -4-picolyl-2-piperazine-tert-butylcarboxamide MERCK & CO INC (US) 1998-06-03 CN disclosed
CN-1147822-A Reactor blend polypropylene, process for the preparation thereof and process for preparing metallocene ligands MONTELL TECHNOLOGY COMPANY BV (NL) 1997-04-16 CN disclosed
CN-1142827-A HIV protease inhibitors MERCK & CO INC (US) 1997-02-12 CN disclosed
CN-1123796-A Process for the preparation of amorphous propylene polymers SPHERILENE SPA (IT) 1996-06-05 CN disclosed