Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | S100B | P04271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516708 | 0.83 | MAPT (0.50) | LGMNMAPTLMNAHTTKDM4E | |
| SCHEMBL2450403 | 0.80 | MAPT (0.63) | LGMNMAPTLMNAHTTKDM4E | |
| SCHEMBL27499322 | 0.74 | KDM1A (0.36) | MAPTLMNAHTTKDM4ENSD2 | |
| SCHEMBL6052510 | 0.74 | KDM4E (0.49) | LGMNMAPTLMNAHTTKDM4E | |
| SCHEMBL27500564 | 0.74 | MAPT (0.40) | LGMNMAPTLMNAHTTKDM4E | |
| SCHEMBL2979851 | 0.73 | MAPT (0.56) | LGMNMAPTLMNAHTTKDM4E | |
| SCHEMBL5461329 | 0.72 | MAPT (0.59) | LGMNMAPTLMNAHTTKDM4E | |
| SCHEMBL3184909 | 0.72 | CHUK (0.44) | MAPTKDM4ETSHRCASP1CASP7 | |
| SCHEMBL81970 | 0.70 | MAPT (0.63) | LGMNMAPTLMNAHTTKDM4E | |
| SCHEMBL15938567 | 0.68 | CHUK (0.47) | MAPTKDM4ETSHRCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1230421-C | Amide compound and pharmaceutical use thereof | MITSUBISHI CHEM CORP (JP) | 2005-12-07 | — | — | CN | disclosed |
| CN-1346348-A | Amide compound and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2002-04-24 | — | — | CN | disclosed |