Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.66 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650594 | 0.92 | PPARG (0.78) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL27448720 | 0.89 | PPARG (0.68) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL6308137 | 0.86 | PPARG (0.83) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL6301327 | 0.86 | PPARG (0.83) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL7652275 | 0.86 | PPARG (0.80) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6134679 | 0.85 | PPARG (0.81) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL6301610 | 0.85 | PPARG (0.81) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL7651430 | 0.85 | PPARG (0.74) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL27451044 | 0.85 | PPARG (0.68) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6303482 | 0.83 | PPARG (0.79) | PPARGRORCHDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1135224-C | Benzimidazole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-01-21 | — | — | CN | disclosed |
| CN-1268123-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-27 | — | — | CN | disclosed |