SCHEMBL27508316

SCHEMBL27508316

C[C](O)N1CCN(C(C)=O)CC1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
PIK3CD O00329 1/20 0.48
KMT2A Q03164 2/20 0.45
CASP6 P55212 1/20 0.42
GFER P55789 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
EPHX2 P34913 1/20 0.39
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14407779 0.87 CYP1A2 (0.77) CYP1A2TDP1SMN1; SMN2KDM4EPIK3CD
SCHEMBL860793 0.87 CYP1A2 (0.77) CYP1A2TDP1SMN1; SMN2KDM4EPIK3CD
SCHEMBL37407 0.87
SCHEMBL27683244 0.84
SCHEMBL2991648 0.82 CYP1A2 (0.62) CYP1A2TDP1SMN1; SMN2KDM4EPIK3CD
SCHEMBL1197207 0.79 CYP1A2 (0.65) CYP1A2TDP1SMN1; SMN2KDM4EPIK3CD
SCHEMBL27953613 0.79 CYP1A2 (0.65) CYP1A2TDP1SMN1; SMN2KDM4EPIK3CD
SCHEMBL13925516 0.77 CYP1A2 (1.00) CYP1A2TDP1SMN1; SMN2KDM4EPIK3CD
SCHEMBL9183693 0.77 CYP1A2 (0.62) CYP1A2TDP1SMN1; SMN2KDM4EPIK3CD
SCHEMBL10401946 0.77 CYP1A2 (0.62) CYP1A2TDP1SMN1; SMN2KDM4EPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1136556-A Aromatic group substituted W-amino alkyl amide and alkyl amide CIBA GEIGY CO LTD (CH) 1996-11-27 CN disclosed