Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CTSD | P07339 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.61 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489150 | 0.90 | KLKB1 (0.63) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL6814805 | 0.84 | GAA (0.69) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL995085 | 0.84 | GAA (0.77) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL4955903 | 0.83 | GAA (0.67) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL4955884 | 0.83 | GAA (0.67) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL4958300 | 0.82 | GAA (0.71) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL94829 | 0.82 | GAA (0.71) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL27657640 | 0.82 | GAA (0.71) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL4958310 | 0.82 | GAA (0.71) | GAASMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL1010241 | 0.81 | GAA (0.69) | GAASMN1; SMN2HTTNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | disclosed |
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | disclosed |