Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 20/20 | 0.82 |
| ▸ | EDNRB | P24530 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631810 | 0.91 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL5206860 | 0.90 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4630737 | 0.88 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7343101 | 0.88 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL27514463 | 0.88 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL27514464 | 0.86 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL4631331 | 0.86 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL5210566 | 0.86 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4630720 | 0.85 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL5211878 | 0.85 | EDNRA (0.83) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1253560-A | Sulfonamides for the treatment of endothelin mediated diseases | TEXA BIOTECHNOLOGY CORP (US) | 2000-05-17 | — | — | CN | claimed |
| CN-1253560-A | Sulfonamides for the treatment of endothelin mediated diseases | TEXA BIOTECHNOLOGY CORP (US) | 2000-05-17 | — | — | CN | disclosed |