Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.61 |
| ▸ | ITGAL | P20701 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200349 | 0.91 | ITGB2 (0.76) | ITGB2ICAM1ITGAL | |
| SCHEMBL27475640 | 0.84 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL27475311 | 0.84 | ITGB2 (0.83) | ITGB2ICAM1ITGAL | |
| SCHEMBL27551799 | 0.84 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL27491649 | 0.82 | ITGAL (0.81) | ITGB2ICAM1ITGAL | |
| SCHEMBL27514900 | 0.81 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL27474410 | 0.81 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL27490591 | 0.81 | ITGAL (0.66) | ITGB2ICAM1ITGAL | |
| SCHEMBL6736459 | 0.80 | ITGAL (0.84) | ITGB2ICAM1ITGAL | |
| SCHEMBL28761950 | 0.80 | ITGAL (0.84) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | claimed |
| CN-1955164-A | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LAB (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1680338-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | disclosed |