Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.57 |
| ▸ | CA1 | P00915 | 10/20 | 0.57 |
| ▸ | CA9 | Q16790 | 9/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780030 | 0.89 | CA1 (0.56) | CA2CA1CA9CXCR2CXCR1 | |
| SCHEMBL8821206 | 0.89 | CA1 (0.56) | CA2CA1CA9CXCR2CXCR1 | |
| SCHEMBL27319143 | 0.88 | CXCR2 (0.53) | CA2CA1CA9CXCR2CXCR1 | |
| SCHEMBL27804335 | 0.87 | CA1 (0.54) | CA2CA1CA9CXCR2CXCR1 | |
| SCHEMBL28807949 | 0.87 | CA1 (0.54) | CA2CA1CA9CXCR2CXCR1 | |
| SCHEMBL28043817 | 0.87 | CA1 (0.54) | CA2CA1CA9CXCR2CXCR1 | |
| SCHEMBL6923665 | 0.87 | CA1 (0.54) | CA2CA1CA9CXCR2CXCR1 | |
| SCHEMBL1128833 | 0.87 | CA1 (0.54) | CA2CA1CA9CXCR2CXCR1 | |
| Iodide SCHEMBL3347577 | 0.87 | CA1 (0.54) | CA2CA1CA9CXCR2CXCR1 | |
| Methane SCHEMBL27573607 | 0.87 | CA1 (0.54) | CA2CA1CA9CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434284-A | A kind of molten wadding thing of clay for carbon tetrachloride processing, preparation method and applications | 徐州工程学院 | 2017-12-05 | — | — | CN | claimed |
| CN-110446700-A | Compound | GLAXOSMITHKLINE IP DEV LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-110139852-A | Tricyclic heterocyclic derivatives and use thereof | 奥克兰联合服务有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-106715416-B | The pyrrolopyridine regulator and its application method that the methyl and trifluoromethyl of RORC2 replaces | 辉瑞大药厂 | 2019-07-23 | — | — | CN | disclosed |
| CN-109415320-A | The inhibitor and its application method of indole amine 2,3-dioxygenase | 百时美施贵宝公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109414420-A | The inhibitor and its application method of indole amine 2,3-dioxygenase | 百时美施贵宝公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109414421-A | The inhibitor and its application method of indole amine 2,3-dioxygenase | 百时美施贵宝公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109348714-A | The inhibitor and its application method of indole amine 2,3-dioxygenase | 百时美施贵宝公司 | 2019-02-15 | — | — | CN | disclosed |
| CN-109311816-A | Inhibitors of indoleamine 2, 3-dioxygenase and methods of use thereof | 百时美施贵宝公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-108368129-A | New modification macrocyclic compound | 拜耳医药股份有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-102648174-A | Novel arylated camphenes, process for their preparation and their use | YISSUM RES DEV CO (IL) | 2012-08-22 | — | — | CN | disclosed |
| CN-101583616-B | Aza-benzothiophenyl compounds and methods of use | GENENTECH INC | 2012-05-30 | — | — | CN | disclosed |
| CN-101151262-B | Substituted piperidines | SPEEDEL EXPERIMENTA AG | 2011-07-06 | — | — | CN | disclosed |
| CN-101730692-A | Pyridazinone derivatives useful as glucan synthase inhibitors | SCHERING CORP | 2010-06-09 | — | — | CN | disclosed |
| CN-101605794-A | Azabenzofuranyl compounds and methods of use | GENENTECH INC (US) | 2009-12-16 | — | — | CN | disclosed |
| CN-101583616-A | Aza-benzothiophenyl compounds and methods of use | GENENTECH INC (US) | 2009-11-18 | — | — | CN | disclosed |
| CN-101490024-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |
| CN-101356164-A | Novel compounds | ASTRAZENECA AB (SE) | 2009-01-28 | — | — | CN | disclosed |
| CN-1942463-A | 2-aminopyridine derivative | ASTELLAS PHARMA INC (JP) | 2007-04-04 | — | — | CN | disclosed |
| CN-1232398-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-10-20 | — | — | CN | disclosed |