Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.77 |
| ▸ | F2 | P00734 | 3/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.66 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.66 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170828 | 0.92 | F10 (0.74) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5383621 | 0.86 | F10 (0.64) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5390738 | 0.85 | F10 (0.77) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8169873 | 0.82 | F10 (0.91) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8169948 | 0.79 | F10 (0.67) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8162653 | 0.78 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7352218 | 0.77 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8170658 | 0.76 | F10 (0.76) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28824022 | 0.74 | F10 (0.56) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8157129 | 0.74 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1259942-A | Novel guanidine mimics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2000-07-12 | — | — | CN | claimed |
| CN-1259942-A | Novel guanidine mimics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2000-07-12 | — | — | CN | disclosed |