Tetranitromethane

Tetranitromethane

SCHEMBL27519009

NC(Cc1ccc(O)c([N+](=O)[O-])c1)C(=O)O.O=[N+]([O-])C([N+](=O)[O-])([N+](=O)[O-])[N+](=O)[O-]

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 4/20 0.58
SLC7A5 Q01650 3/20 0.57
ALOX15 P16050 2/20 0.57
HSD17B10 Q99714 2/20 0.57
KDM4E B2RXH2 1/20 0.57
USP2 O75604 1/20 0.57
EGFR P00533 1/20 0.57
LCK P06239 1/20 0.57
FYN P06241 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
PTGS1 P23219 1/20 0.57
HTR2A P28223 1/20 0.57
PTGS2 P35354 1/20 0.57
RECQL P46063 1/20 0.57
HIF1A Q16665 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
GRM8 O00222 3/20 0.48
GRM6 O15303 3/20 0.48
GRM7 Q14831 2/20 0.48
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1589004 0.93 SLC7A5 (0.65) GRM4SLC7A5ALOX15HSD17B10KDM4E
SCHEMBL38175 0.93 SLC7A5 (0.65) GRM4SLC7A5ALOX15HSD17B10KDM4E
SCHEMBL28040459 0.93 SLC7A5 (0.65) GRM4SLC7A5ALOX15HSD17B10KDM4E
SCHEMBL28040458 0.93 SLC7A5 (0.65) GRM4SLC7A5ALOX15HSD17B10KDM4E
SCHEMBL108202 0.93 SLC7A5 (0.65) GRM4SLC7A5ALOX15HSD17B10KDM4E
SCHEMBL4502044 0.93 SLC7A5 (0.65) GRM4SLC7A5ALOX15HSD17B10KDM4E
Phenol SCHEMBL29144981 0.87 GRM4 (0.58) GRM4SLC7A5ALOX15HSD17B10KDM4E
SCHEMBL16915278 0.86 GRM4 (0.57) GRM4SLC7A5ALOX15HSD17B10KDM4E
SCHEMBL16915277 0.86 GRM4 (0.57) GRM4SLC7A5ALOX15HSD17B10KDM4E
Norleucine SCHEMBL27238061 0.83 GRM4 (0.59) GRM4SLC7A5ALOX15HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108135963-A Peptides for promoting glucose transport 努里塔斯有限公司 2018-06-08 CN disclosed
CN-1659184-B Prothrombin activating protein LIAONING NUOKANG BIO PHARMACEUTICAL CO LTD 2014-11-19 CN disclosed
CN-102325788-B Cancer-targeting peptides and their use in cancer therapy ACADEMIA SINICA 2014-08-13 CN disclosed
CN-103834665-A Use of anti-fungal defensins HEXIMA LTD 2014-06-04 CN disclosed
CN-101027546-B Biosensor using whispering gallery modes in microspheres GENERA BIOSYSTEM PTY LTD 2013-09-25 CN disclosed
CN-103328499-A Immune-modulating agents and uses therefor UNIV SYDNEY TECH 2013-09-25 CN disclosed
CN-102206276-B Humanized antibodies derived from DD-3B6/22, specific for the D-dimer fragment of fibrin AGEN BIOMEDICAL LTD 2013-07-17 CN disclosed
CN-103038351-A Vitronectin-keratinocyte growth factor chimeras UNIV QUEENSLAND 2013-04-10 CN disclosed
CN-1541107-B Growth factor complexes QUEENSLAND UNIV OF TECH 2013-03-20 CN disclosed
CN-102940880-A Growth factor complex UNIV QUEENSLAND 2013-02-27 CN disclosed
CN-1680432-A Viral proteins YUNG SHIN PHARM IND CO LTD (CN) 2005-10-12 CN disclosed
CN-1659184-A Prothrombin activating protein UNIV QUEENSLAND (AU) 2005-08-24 CN disclosed
CN-1596264-A Differentially expressed genes related to obesity and type 2 diabetes AUTOGEN RES PTY LTD (AU) 2005-03-16 CN disclosed
CN-1541107-A Growth factor complexes ��ʿ����ѧ 2004-10-27 CN disclosed
CN-1531554-A Humanized antibodies derived from DD-3B 6/22 specific for the D-dimer fragment of fibrin ��������ҽѧ���޹�˾ 2004-09-22 CN disclosed
CN-1494592-A Nucleic acid expressed in hypothalamus or muscle tissue in obese animals ���и��о��ɷ����޹�˾ 2004-05-05 CN disclosed
CN-1419564-A Proteins comprising conserved regions of neisseria meningitidis surface antigen NhhA UNIV QUEENSLAND (AU) 2003-05-21 CN disclosed
CN-1331748-A Recombinant method and reagents therefor MURDOCH INST (AU) 2002-01-16 CN disclosed
CN-1297454-A Novel omega-conotoxin peptides UNIV QUEENSLAND (AU) 2001-05-30 CN disclosed
CN-1284965-A Novel surface proteins of neisseria meningitidis UNIV QUEENSLAND (AU) 2001-02-21 CN disclosed