Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 12/20 | 0.59 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.59 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770665 | 0.92 | MAPK13 (0.61) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 | |
| SCHEMBL27521516 | 0.89 | MAPK13 (0.63) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 | |
| SCHEMBL5769188 | 0.89 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 | |
| SCHEMBL5770702 | 0.87 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 | |
| SCHEMBL5771863 | 0.86 | MAPK13 (0.63) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 | |
| SCHEMBL5770926 | 0.85 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5771126 | 0.85 | MAPK13 (0.62) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 | |
| SCHEMBL5770136 | 0.83 | MAPK13 (0.74) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 | |
| SCHEMBL5772878 | 0.83 | MAPK13 (0.66) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 | |
| SCHEMBL6809860 | 0.83 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100443481-C | Imidazolyl-cyclic acetals | RHONE POULENC RORER LTD (GB) | 2008-12-17 | — | — | CN | disclosed |
| CN-1273584-A | Imidazolyl-cyclic acetals | RHONE POULENC RORER LTD (GB) | 2000-11-15 | — | — | CN | disclosed |