Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL27410134 | 0.98 | KMT2A (0.41) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL4950 | 0.94 | NR1H2 (0.43) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL3962514 | 0.91 | NR1H2 (0.42) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL28994299 | 0.91 | NR1H2 (0.42) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| Selenium SCHEMBL30289776 | 0.91 | NR1H2 (0.42) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL29402664 | 0.91 | NR1H2 (0.42) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| Water SCHEMBL7382263 | 0.91 | NR1H2 (0.42) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10635278 | 0.91 | NR1H2 (0.42) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL22498864 | 0.91 | NR1H2 (0.42) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| Bromide SCHEMBL8589844 | 0.91 | NR1H2 (0.42) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1074216-A | Urea derivative | GLAXO GROUP LTD (GB) | 1993-07-14 | — | — | CN | disclosed |