Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.88 |
| ▸ | CA2 | P00918 | 6/20 | 0.88 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl 4-Methoxybenzoate SCHEMBL231243 | 0.94 | CA1 (1.00) | CA1CA2MAPTKMT2AKDM4E | |
| Methyl 4-Methoxybenzoate SCHEMBL27405603 | 0.91 | CA1 (0.95) | CA1CA2MAPTKMT2AKDM4E | |
| Methyl 4-Methoxybenzoate SCHEMBL28248974 | 0.89 | CA1 (0.91) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL269558 | 0.88 | CA1 (0.88) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL16604876 | 0.88 | CA1 (0.88) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL2273711 | 0.88 | CA1 (0.88) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL2188276 | 0.88 | CA1 (0.88) | CA1CA2MAPTKMT2AKDM4E | |
| Methyl 4-Methoxybenzoate SCHEMBL8374556 | 0.86 | CA1 (0.84) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL13038154 | 0.86 | CA1 (0.84) | CA1CA2MAPTKMT2AKDM4E | |
| Methyl 4-Methoxybenzoate SCHEMBL28249391 | 0.86 | CA1 (0.84) | CA1CA2MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1283252-C | Substituted 4-phenyl-4-[1h-imidazol-2-yl]-piperidine derivatives for reducing ischaemic damage | JANSSEN PHARMACEUTICA NV (BE) | 2006-11-08 | — | — | CN | disclosed |
| CN-1568186-A | Substituted 4-phenyl-4-[1h-imidazol-2-yl]-piperidine derivatives for reducing ischaemic damage | JANSSEN PHARMACEUTICA NV (BE) | 2005-01-19 | — | — | CN | disclosed |