Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28584905 | 0.88 | MAPK1 (0.81) | MAPK1ALDH1A1ALOX15TSHRKMT2A | |
| Bicarbonate SCHEMBL28837071 | 0.88 | MAPK1 (0.81) | MAPK1ALDH1A1ALOX15TSHRKMT2A | |
| Acrylamide SCHEMBL28336053 | 0.87 | MAPK1 (0.61) | MAPK1ALDH1A1ALOX15TSHRHTT | |
| SCHEMBL8883023 | 0.82 | MAPK1 (0.53) | MAPK1ALDH1A1ALOX15TSHRHTT | |
| Acetone SCHEMBL27544937 | 0.82 | MAPK1 (0.77) | MAPK1ALDH1A1ALOX15TSHRKMT2A | |
| Acetic Acid SCHEMBL28355097 | 0.82 | MAPK1 (0.77) | MAPK1ALDH1A1ALOX15TSHRKMT2A | |
| Hydrogen Peroxide SCHEMBL22163808 | 0.82 | MAPK1 (0.94) | MAPK1ALDH1A1ALOX15TSHRKMT2A | |
| SCHEMBL27810773 | 0.81 | MAPK1 (0.63) | MAPK1ALDH1A1ALOX15TSHRHTT | |
| Methacrylic Acid SCHEMBL27561274 | 0.81 | MAPK1 (0.63) | MAPK1ALDH1A1ALOX15TSHRHTT | |
| Methyl Alcohol SCHEMBL28217041 | 0.80 | MAPK1 (0.90) | MAPK1ALDH1A1ALOX15TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1309778-C | Preparation for ternary ethylene-propylene rubber reinforced by nano calcium carbonate | UNIV SHANGHAI JIAOTONG (CN) | 2007-04-11 | — | — | CN | disclosed |
| CN-1709960-A | Preparation for ternary ethylene-propylene rubber reinforced by nano calcium carbonate | UNIV SHANGHAI JIAOTONG (CN) | 2005-12-21 | — | — | CN | disclosed |