Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.59 |
| ▸ | PI4KA | P42356 | 2/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.46 |
| ▸ | AHCY | P23526 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27460111 | 0.99 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL12922451 | 0.79 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL12922453 | 0.78 | ADORA2A (0.67) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL14822332 | 0.78 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL19841 | 0.77 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL27438039 | 0.77 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL13952171 | 0.76 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL15214233 | 0.76 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL233405 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL29387721 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1125946-A | Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines | MERRELL DOW PHARMA (US) | 1996-07-03 | — | — | CN | claimed |
| CN-1125946-A | Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines | MERRELL DOW PHARMA (US) | 1996-07-03 | — | — | CN | disclosed |