Propylene Oxide

Propylene Oxide

SCHEMBL27541663

C=CC.CC1CO1.CCC

nearest known ligand 0.36

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
CHRM2 P08172 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM3 P20309 2/20 0.33
CHRM4 P08173 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL11051700 0.91 TDP1 (0.42) TDP1CHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL1907901 0.91
Propylene Oxide SCHEMBL10795929 0.88
Propylene Oxide SCHEMBL8165755 0.85
Propylene Oxide SCHEMBL27414072 0.85
Propylene Oxide SCHEMBL9859778 0.84
Propylene Oxide SCHEMBL10391364 0.83 TDP1 (0.33) TDP1CHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL22362337 0.82 TDP1 (0.36) TDP1
Propylene Oxide SCHEMBL17849013 0.81
Propylene Oxide SCHEMBL11181636 0.78 TDP1 (0.33) TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1280280-C Process for continuously producing alkylene oxide DOW GLOBAL TECHNOLOGY INC (US) 2006-10-18 CN disclosed
CN-1446206-A Process for continuous production of olefinic oxide DOW GLOBAL TECHNOLOGY INC (US) 2003-10-01 CN disclosed
CN-1388805-A Integrated process for the prepatation of epoxides POLIMARY EUROP S P A (IT) 2003-01-01 CN disclosed