Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543785 | 0.85 | TRPV1 (0.40) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27543784 | 0.82 | TRPV1 (0.39) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27564022 | 0.80 | TRPV1 (0.40) | TSHRKMT2AMEN1MAPTTRPV1 | |
| SCHEMBL14086462 | 0.74 | TRPV1 (0.38) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3281623 | 0.74 | KMT2A (0.39) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13385466 | 0.72 | SMO (0.42) | TSHRKMT2AMEN1LMNANPSR1 | |
| SCHEMBL344327 | 0.72 | TSHR (0.46) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL14500980 | 0.72 | CDK2 (0.35) | TSHRALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL5250958 | 0.72 | TRPV1 (0.35) | TSHRALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL4814547 | 0.72 | TRPV1 (0.35) | TSHRKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1312134-C | 5-phenylpyrimidine compounds, compositions comprising them, processes for their preparation and their use | BASF AG (DE) | 2007-04-25 | — | — | CN | claimed |