Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.65 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.63 |
| ▸ | EP300 | Q09472 | 1/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074514 | 1.00 | CETP (0.65) | CETPSOAT1EP300P2RX7HDAC3 | |
| SCHEMBL24420606 | 0.94 | CETP (0.63) | CETPSOAT1ALDH1A1ALOX12KMT2A | |
| SCHEMBL14282881 | 0.90 | CETP (0.53) | CETPSOAT1EP300P2RX7HDAC3 | |
| SCHEMBL4139016 | 0.88 | SOAT1 (0.68) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL7636178 | 0.88 | SOAT1 (0.68) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL7634493 | 0.88 | SOAT1 (0.68) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL5840193 | 0.88 | SOAT1 (0.68) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL2183707 | 0.88 | SOAT1 (0.68) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL1042215 | 0.88 | SOAT1 (0.68) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL7629650 | 0.88 | SOAT1 (0.68) | CETPSOAT1EP300HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152907-A | 2-acylaminopropanol compounds and pharmaceutical compositions thereof | SEIKAGAKU KOGYO CO LTD (JP) | 1997-06-25 | — | — | CN | disclosed |