1,3-Dicyclohexylurea

1,3-Dicyclohexylurea

SCHEMBL2755

O=C(NC1CCCCC1)NC1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 14/20 1.00
EPHX2 P34913 5/20 1.00
NPC1 O15118 3/20 1.00
RAB9A P51151 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
KDM4E B2RXH2 2/20 1.00
ALDH1A1 P00352 2/20 1.00
CYP3A4 P08684 1/20 1.00
MAPT P10636 1/20 0.70
KMT2A Q03164 2/20 0.63
MEN1 O00255 1/20 0.61
CYP2D6 P10635 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12196125 1.00 EPHX1 (1.00) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL12196126 1.00 EPHX1 (1.00) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL12196101 1.00 EPHX1 (1.00) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL5265524 1.00 EPHX1 (1.00) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL23960132 1.00 EPHX1 (1.00) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL15093798 1.00 EPHX1 (1.00) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL24308701 1.00 EPHX1 (1.00) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL24308699 1.00 EPHX1 (1.00) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL15277631 0.97 EPHX1 (0.94) EPHX1EPHX2NPC1RAB9ASMN1; SMN2
SCHEMBL11046265 0.97 EPHX1 (0.94) EPHX1EPHX2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17715 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005449-A Fluorinated polymorpholine mitochondria targeting micelle and preparation method and application thereof 国科大杭州高等研究院 2026-05-12 CN claimed
US-20260103447-A1 METHODS FOR PREPARING PSMA CONJUGATES ENDOCYTE, INC. 2026-04-16 US claimed
EP-4638538-A1 LIQUID RHEOLOGY CONTROL AGENT BYK-Chemie GmbH (DE) 2025-10-29 EP claimed
US-20250258158-A1 BIOMARKERS FOR DETECTION AND TREATMENT ASSESSMENT OF INFECTIOUS DISEASES AND DISORDERS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2025-08-14 US claimed
CN-119978051-B Ascorbic acid polypeptide derivative and preparation method and application thereof 上海中翊日化有限公司 2025-06-24 CN claimed
WO-2025122010-A1 A METHOD FOR PURIFYING A MODIFIED GELATIN SENTRYX B.V. (NL) 2025-06-12 WO claimed
CN-119978051-A Ascorbic acid polypeptide derivative and preparation method and application thereof 上海中翊日化有限公司 2025-05-13 CN claimed
CN-119822970-A Method for recycling cyclohexylamine and simultaneously producing 2-benzimidazolone as byproduct from DCU 济南大学 2025-04-15 CN claimed
CN-119775066-A Organic selenium microbial fertilizer and preparation method thereof 北京中农硒谷科技有限公司 2025-04-08 CN claimed
CN-119391094-A Parallel reinforcement type overhead insulated cable 云南云缆电缆(集团)有限公司 2025-02-07 CN claimed
EP-0271552-B1 Derivatives of all-trans- and 13-cis retinoic acid and methods for preparing same WISCONSIN ALUMNI RES FOUND (US) 1993-10-27 EP claimed
US-5142062-A Using phosphoric acid ROHM GMBH CHEMISCHE FABRIK (DE) 1992-08-25 US claimed
US-5076973-A Cell growth inhibitor;leukemia ARIZONA BOARD OF REGENTS (US) 1991-12-31 US claimed
US-4966965-A Method for preparing all-trans retinoyl CoA WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1990-10-30 US claimed
US-4931509-A EPOXY-CONTAINING MONOMER; EXCELLENT VULCANIZING WITH UREAS, QUATERNARY AMMONIUM AND PHOSPHONIUM SALTS AND POLYCARBOXYLIC ACIDS OR ANHYDRIDES NIPPON ZEON CO., LTD. (JP) 1990-06-05 US claimed
US-4870181-A AMIDATION OF 3-AMINOQUINUCLIDINE SALT A. H. ROBINS COMPANY, INCORPORATED (US) 1989-09-26 US claimed
US-4841038-A Method for preparing coenzyme a esters of all-trans- and 13-cis retinoic acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1989-06-20 US claimed
WO-1987007604-A1 DERIVATIVES OF ALL-TRANS- AND 13-CIS RETINOIC ACID AND METHODS FOR PREPARING SAME WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1987-12-17 WO claimed
EP-0064714-B1 PROCESS FOR DESENSITIZING HYDROXYBENZOTRIAZOLES AND HYDROXY-OXOBENZOTRIAZINES HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-21 EP claimed
US-4288609-A ESTERIFICATION OF ADAMANTANECARBOXYLIC ACID WITH A TERTIARY AMINO ALCOHOL AND QUATERNIZATION OF THE ESTERIFIED PRODUCT ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1981-09-08 US claimed