SCHEMBL27550385

SCHEMBL27550385

O=C(O)C1=CC=CC(=C(C(F)(F)F)C(F)(F)F)C1C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OAT P04181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27816231 0.71
SCHEMBL27501079 0.71
SCHEMBL28234220 0.69
SCHEMBL9149757 0.61 MAPT (0.34)
SCHEMBL27434209 0.61
SCHEMBL27704000 0.57 TSHR (0.38)
SCHEMBL1081929 0.56 TSHR (0.33)
SCHEMBL4243463 0.56
SCHEMBL11094420 0.56
SCHEMBL6205007 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1324037-C Multimer forms of mono- and bis-acylphosphine oxides CIBA SC HOLDING AG (CH) 2007-07-04 CN disclosed
CN-1659175-A Multimeric forms of monoacyl and diacylphosphine oxides CIBA SC HOLDING AG (CH) 2005-08-24 CN disclosed