Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737341 | 0.96 | F10 (0.77) | F10ATM | |
| Hydrochloric Acid SCHEMBL5733561 | 0.95 | F10 (0.75) | F10ATM | |
| Acetic Acid SCHEMBL27550419 | 0.91 | F10 (0.59) | F10ATMF2 | |
| Acetic Acid SCHEMBL28744428 | 0.90 | F10 (0.74) | F10ATM | |
| Acetic Acid SCHEMBL27525139 | 0.89 | F10 (0.57) | F10F2 | |
| Acetic Acid SCHEMBL27552344 | 0.89 | F10 (0.60) | F10 | |
| Acetic Acid SCHEMBL27530032 | 0.88 | F10 (0.59) | F10 | |
| Acetic Acid SCHEMBL27568115 | 0.87 | F10 (0.64) | F10ATM | |
| SCHEMBL7074239 | 0.87 | F10 (0.63) | F10ATM | |
| Acetic Acid SCHEMBL27525160 | 0.86 | F10 (0.62) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1272107-A | Benzamidine derivatives as factor Xa inhibitors | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |